GNB Limited is a specialist Statistical Consultancy, founded in 1995 by Dr. Les Huson, Consultant and Lecturer in Medical Statistics. GNB works with clients in the pharmaceutical and biotechnology sectors, providing services in all aspects of statistical work related to the design and analysis of clinical trials. Our services have been instrumental in helping clients to achieve timely US and European Drug Marketing Approvals, and the results of our collaborative work continue to be published in major international peer-reviewed journals.

Services include planning of drug development programmes and individual trial designs, protocol writing, sample size and power calculations, preparation of statistical analysis plans and analysis software, data analysis, tabulation, listing and graphics, significance testing and estimation, statistical interpretation and report writing, clinical data mining and exploratory statistical analysis. We have a special interest in Bayesian methodology and the design and analysis of adaptive clinical trials, and we also provide courses and training in statistical methods.


A Phase II Crossover Trial An Exploratory Trial in a Rare Disease Adaptive Dose Finding and Trial Ethics Bayesian Logistic Regression Clinical trial of HIV treatment Clinical Trial of Influenza Prophylaxis A cluster-randomised clinical trial
What is an adaptive clinical trial? Training on Bayesian Dose-Response Methods